Architecture – Whimble Gardens Wed, 02 Jun 2021 09:01:36 +0000 en-US hourly 1 Architecture – Whimble Gardens 32 32 Master’s Degree Programs in Architecture Making Sustainable Leaders Wed, 02 Jun 2021 08:48:17 +0000

Architects are faced with an enigma. The built environment is responsible for much of the energy – it accounts for around 40% of global energy consumption. It emits 30% of energy-related greenhouse gas emissions – the manufacture of steel and concrete generates around 8% of the world’s anthropogenic carbon dioxide emissions – in addition to generating waste and d ” use natural resources.

Yet they are ready to do more. They are building a future where 68% of the world’s population will live in cities by 2050, an increase from the current figure which hovers around 50% today. They need to build more houses, roads and other infrastructure. In some countries, entire cities the size of Chicago would have to be built to provide enough housing.

Their task is to reach both without destroying the planet to a point of no return. The solution? Design and build in a greener, fairer and more sustainable way. A Master of Architecture is a prerequisite and these universities offer the best in the United States:

Roger Williams University: School of Architecture

Little Master of Architecture in the United States prepare students for career success as effectively as School of Architecture, Art and Historical Preservation at Roger Williams University. Here, a paid internship or assistantship is guaranteed – for every M.Arch student in this NAAB accredited and designated STEM program. Each semester, the studios are taught by a Teaching office in residence, comprising a group of chief architects from a leading firm in Boston, New York or the Northeastern United States – an initiative unique to the university.

Source: Shutterstock

On campus, students work with Samsung Flat Panel Monitors, coupled with anytime access to the latest versions of software and advanced applications (including AutoCAD, Revit, Rhino, Maya, Adobe Creative Suite, among others). Off campus, study abroad possibilities let them travel to Beijing, the frenetic capital of China and its fantastic new sculptural monuments, or to Barcelona with the genius of Gaudi dotted in the Catalan capital.

A RWU educational journey extends far beyond the walls of a traditional classroom. With the Career investment program – until recently, the only program in the United States offering this kind of opportunity for all students – it can accommodate one as an internship at Safdie Architects in Shanghai, Wodiczko + Bonder in Cambridge and HOK in New York. This research and professional experience is not only paid, but, more importantly, convincing.

A location in Bristol, Rhode Island – one of America’s busiest architectural corridors between Boston and New York – allows RWU to provide such dynamic opportunities. As students explore New England’s quintessential city of Bristol, which RWU calls home – with unique shops, restaurants and waterfront galleries, plus miles of bike and Colt State trails. Park nearby – they are close to some of the country’s most enviable career opportunities. They have unprecedented access to hundreds of architectural firms across the region, the doors of which are opened by the Career Investment Program.

University of Florida: School of Architecture

Florida is poised for rapid growth, which will take place in sensitive natural ecologies, fluctuating tourism, a humid and hot climate, and widespread threats from coastal hurricanes, among others. It will address it by becoming host to the third largest population in the United States.

Master of Architecture

Gainesville, Florida, where nature and culture meet, is home to the University of Florida School of Architecture. Source: University of Florida: School of Architecture

The University of Florida School of Architecture is uniquely positioned to meet these challenges. It has, to its advantage, studio design methodologies working with a new generation of experts in engineering, ecology, business, anthropology, energy, fine arts, medicine, and construction.

It is led by a team of faculty members and students, who have won international, national, state and local design awards. They regularly publish and receive national, state and local grants for research-based learning and service design projects.

Registering for a Master of Architecture (M.Arch) here implies benefiting from the above features and more. Students will earn a professional degree accredited by the National Architectural Accrediting Board (NAAB), the degrees you need to obtain a registered architect’s license in the United States, Canada, and Mexico. Study abroad opportunities in East Asia and Mexico are also available.

Three streams are offered for the first NAAB-accredited professional master’s degree in architecture to cater to those with or without a pre-professional degree, as well as those with an accredited professional degree.

Institute of Architecture of Southern California

Offering undergraduate, graduate and graduate programs, SCI-Arc is strategically housed in the historic Santa Fe Freight Depot located in the Arts District of Los Angeles. Architectural monuments such as the Walt Disney Concert Hall, Chinatown and the Mayan Theater surround it; on campus, it’s an integrated suite of resources that support academic progress and experimentation.

Master of Architecture

SCI Arc is located in the Arts District of Los Angeles. Source: Institute of Architecture of Southern California – Sci Arc

Here, students are exposed to artists, practitioners, historians, theorists and even movie stars. They are trained not only to be architects, but to push boundaries as designers and problem solvers in general. Following in the footsteps of Renaissance genius Leonardo da Vinci and Pritzker Prize winner Hans Hollein, SCI-Arc graduates are recognized for their interdisciplinarity between the arts and sciences.

SCI-Arc offers two NAAB-accredited Master of Architecture (M.Arch) programs. M.Arch 1 is open to applicants with a bachelor’s degree or equivalent degree in any field of study. You will acquire the intellectual foundations, design expertise and technical skills necessary for the professional practice of architecture.

M.Arch 2 is designed for applicants who have obtained a Bachelor of Science in Architecture, Bachelor of Arts in Architecture or Bachelor of Architecture degree. You will build on previous architectural education using contemporary tools and techniques that will broaden their experience in digital design, conceptualization and manufacturing. Both master’s degrees merge a spirit of open inquiry with an encouragement to respond to changes in society, technology and culture.

University of Texas at Austin: School of Architecture

Students at the University of Texas at the Austin School of Architecture (UTSOA) are uniquely positioned to gain first-hand experience in a growing and rapidly changing built environment. UTSOA is part of one of the world’s leading public research universities with more than 170 fields of study, providing an environment conducive to multidisciplinary learning. Its setting? Austin, Texas, a fast growing American city with a fast growing creative community and an entrepreneurial spirit.

Master of Architecture

UTSOA is located in Austin, Texas, known as the Live Music Capital of the World. Source: University of Texas at Austin: Facebook School of Architecture

As for the programs, they promote intellectual ambition and cultural relevance in architectural production. You can expect an integrated and cohesive design studio model where dialogue, collaboration and risk-taking are encouraged.

Since its founding in 1909, UTSOA has been one of the country’s most distinguished schools of architecture. In the 2016-17 DesignIntelligence survey, it was ranked sixth for its undergraduate architecture program and 12th for its graduate architecture program.

UTSOA offers a Masters in Architecture that meets the professional degree requirements for registration as an architect. It is aimed at two categories of candidates: those who enter either without academic training in architecture, or with a “pre-arch” baccalaureate in four years and who wish to enter the profession of architect. The program includes an optional certificate of specialization in historic preservation, sustainable design, urban design, as well as an optional and transcribable graduate certificate in Latin American architecture.

* Some of the schools featured in this article are Business Partners of Study International

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AIM Architecture was crowned winner of the 2021 AR Future Project Awards | New Tue, 01 Jun 2021 23:57:00 +0000

The winners of The 2021 Architectural Review Future Project Awards have been announced and AIM Architecture has been crowned the Grand Winner for its FX Mayr Wellness Eco Retreat project in Wenzhou, China. The company also won the hospitality and leisure award with the project.

Showcasing projects from around the world, this awards program celebrates excellence in unbuilt and incomplete projects.

A large number of notable companies were awarded in the competition. The Mind Play Award was won by OPEN Architecture for its work on the Sun Tower in Yantai, China, and the Sustainability Award went to Zaha Hadid Architects for her Forest Green Rovers Eco Park stadium in Stroud, UK.

Other winners include Stantec in the Cultural Regeneration category for their work on the Musée du Fleuve in Niamey, Niger; Condition_Lab in the Residential category for their Mutating House project in Hunan province, China; Acton Ostry Architects Inc. in the Office / Office Led Development award for their work on Industrial Long Wood in Vancouver, Canada.

As said in The architecture review press release, “Combined, the winners and all finalists of this year’s AR Future Project Awards present examples of innovative and outstanding architecture that successfully meet the development case and also consider the full impact and contribution that ‘they will have on the communities around them. ”

This year’s jury included Christina Seilern, Roger Zogolovitch, Peter Stewart, Jeremy Melvin and Paul Finch.

The full list of winners is listed below or can be viewed here, along with recommended projects.

2021 winners

Mixed-use commercial – The JellyTower – Social Condenser and Fun Palace, Berlin, Germany by CSMM – architecture matters

Community and civic – Park of Future Generations SAKHA_Z, Yakutsk, Russia by Atrium Architecture

Cultural regeneration – River Museum, Niamey, Niger by Stantec

New and old – British Oil Mill, Mersin, Turkey by ANB Architects + Stüdyo Nüve + Onur Yüncü Architects

Offices / Office led development – Industrial Long Wood, Vancouver, Canada by Acton Ostry Architects Inc.

Regeneration and Masterplanning – Morden Wharf, Greenwich Peninsula, UK by U + I

Residential – Changing house, Hunan province, China by Condition_Lab

Development focused on purchasing and retail – Jingumae Pilgrim’s Passage Gates, Tokyo, Japan by Key Operation Inc./ Architects

Sport & Stadiums and Sustainability AwardForest Green Rovers Eco Park Stadium, Stroud, UK by Zaha Hadid Architects

High-rise buildings – Barclay, Vancouver, Canada by ACDF Architecture

Urban infrastructure – Hot Heart, Helsinki, Finland by CRA-Carlo Ratti Associati

Mind Game Prize – Sun Tower, Yantai, China by OPEN Architecture

Overall winner and Hotels and Leisure FX Mayr Wellness Eco Retreat, Wenzhou, China by AIM Architecture

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Areen Design Services, HBA, NBBJ, Nelson – The current of Manomet Tue, 01 Jun 2021 06:00:33 +0000

The report entitled “Global Architecture and Interior Design Market: Industry Analysis, Size, Share, Growth, Trends and Forecast 2021-2027”Using various methodologies aims to examine and bring forward in-depth and accurate data regarding the global architecture and interior design market. The report is divided into different well-defined sections to provide the reader with a simple and understandable information document. In addition, each section is elaborated with all the data necessary to acquire knowledge on the market before entering it or strengthening their current implantation. The report is split into: titled “Architecture and Interior Design Market” is an outstanding market study that provides the hottest detail information and in-depth analysis of this market. It offers a comprehensive summary of the market with in-depth information on essential aspects such as current market situation, possible dimensions, quantity and dynamics of this market. This study report produces a comprehensive assessment of the COVID-19 pandemic and its effects on the current market and assesses the potential market outcomes throughout the forecast period, 2021-2028.

The main major competitive players are:

Areen Design Services, HBA, NBBJ, Nelson, Cannon Design, Gensler, CCD, Perkins + Will, SOM, Perkins Eastman, HKS, Callison, DB & B, Wilson Associates, Jacobs, SmithGroupJJR, M Moser Associates, AECOM Technology, Gold Mantis , HOK, Leo A Daly, Stantec, IA Interior Architects.

The latest research report titled “Architecture and Interior Design Market” added by MR Accuracy Reports provides the reader with a comprehensive overview of the architecture and interior design industry and familiarizes them with the latest market trends, challenges, opportunities, industry information and market share. The content of the report includes technology, industry drivers, geographic trends, market statistics, market forecast, raw material / equipment producers and suppliers. The global architecture and interior design market size was US $ xx million and is expected to reach US $ xx million by the end of 2026, with a CAGR of XX between 2021 and 2026.

FREE: sample request is available @

In addition to bringing significant value to users, the report by MR Accuracy Reports focused on the analysis of Porter’s five forces to highlight the broad spectrum of the market in terms of opportunities, threats and challenges. . The information extracted through different business models like SWOT and PESTEL is represented in the form of pie charts, diagrams and other pictorial representations for a better and faster understanding of the facts. The report can be divided into the following main parts.

Growth drivers:

The report provides an accurate and professional study of the business scenarios of the global market. The complex analysis of opportunities, growth drivers and future forecasts are presented in simple and easily understandable formats. The report understands the architecture and interior design market by elaborating the technological dynamics, financial position, growth strategy and product portfolio during the forecast period.


The report is organized on the basis of segmentation and sub-segmentation which is aggregated from primary and secondary research. Segmentation and sub-segmentation is a consolidation of industry segment, segment type, channel segment and many others. Further, the report is developed to provide in-depth information on each segment.

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Promising Regions & Countries Mentioned In The Architecture And Interior Design Market Report:

  • North America (United States)
  • Europe (Germany, France, United Kingdom)
  • Asia-Pacific (China, Japan, India)
  • Latin America (Brazil)
  • The Middle East and Africa

Regional analysis:

The report covers all regions of the world showing regional development status, market volume, size and value. It facilitates valuable regional knowledge from users which will provide a comprehensive competitive landscape of the regional market. Further, the various regional markets along with their size and value are illustrated in detail in the report for accurate information.

Competitive analysis:

The report is organized after a SWOT analysis of the main market leaders. It contains detailed and strategic contributions from global leaders to help users understand the strengths and weaknesses of key leaders. Expert analysts in the field follow players who are presented as leading leaders in the architecture and interior design market. The report also contains the competitive strategy adopted by these market leaders at market value. Their research and development process has been explained well enough by experts in the global architecture and interior design market to help users understand their working process.

Key details and USP of the existing report study:

  • Global market size of architecture and interior design market in terms of volume (K units) and value (USD Million) for the historical period (2016-2020) and projected years (2021-2027)
  • Regionally (North America, Europe, Asia-Pacific, Latin America & Middle East & Africa) market size of Architecture and Interior Design market in terms of volume (K units) and value ( in millions of USD) for the historical period (2016-2020)) and projected years (2021 – 2027)
  • Market size at country level (US, Canada, Germany, UK, France, Spain, Italy, China, Japan, India, South Korea, Southeast Asia, Brazil, Mexico, GCC, Africa South, RoW) of the architecture and interior design market in terms of volume (K units) and value (USD Million) for the historical period (2016-2020) and projected years (2021-2027 )
  • Market size of the type divided into its individual product type (concentration, temperature, combustion, conductivity and others) in terms of volume (K units) and value (USD Million) for the historical period (2016-2020) and projected years (2021-2027))
  • Demand side and supply side perspective and analysis
  • Market share of the company / players / manufacturers / suppliers / service providers
  • Analysis of the competitive landscape, the competition matrix and player positioning
  • Market dynamics, trends, factors affecting the growth of the market in the coming year
  • Top Buyers and End User Analysis
  • Value chain and supply chain analysis, including distribution and sales channels, as well as upstream and downstream integration scenarios
  • Analysis of the manufacturing cost structure
  • Analysis of key raw materials
  • Key pricing strategies adopted in the market
  • Key marketing strategies adopted in the market
  • Analysis of the five forces of carriers
  • SWOT analysis
  • PESTLE analysis

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What the reports provide

  • Complete and in-depth analysis of the parent market
  • Significant changes in market dynamics
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  • Key strategies of the main players
  • Emerging segments and regional markets
  • Testimonials to companies in order to strengthen their presence in the market.

In addition, the research report examines:

  • Competitive businesses and manufacturers in the world market
  • By product type, applications & Growth factors
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Siteless is an architecturally inspired book Sun, 30 May 2021 14:50:00 +0000

A friend of mine gave me a copy of the book, Siteless: 1001 construction forms by François Blanciak as a gift a few years ago, and I often use it for reference images and inspiration for my designs. Although I am not an architect and this is an architecture inspired book, the shapes it contains are great for drawing inspiration, parts of creatures or just fun candy.

Siteless, released in 2008, includes 1,001 different building shapes – “structural pests, chain link towers, ball bearing floors, wavy corners, exponential balconies, radial facades, creeping frames, forensic dwellings” and more. The forms are all drawn freehand and arranged 12 per page, in no particular order. Besides the title of each form, the book contains few words, which I welcome as it allows me to get lost in the forms as a reader. The end of the book shows what building these shapes looks like in real life, at an architectural site in Tokyo.

The book is a great resource for artists and designers who draw things like architecture, interiors, products, etc., and therefore a great reference book to have on hand, but it is also great for drawing. general inspiration. Art students, architects, interior designers, furniture designers, product designers and graphic designers take note: this is a great book to have on hand and I highly recommend it

From the MIT Press website:

Its author, a young French architect practicing in Tokyo, admits that he “did not do this out of respect for the architecture, but rather out of deep boredom with the discipline, as a sort of compulsive reaction”. What would happen if architects freed their minds from the constraints of site, schedule and budget? he asks. The result is a book saturated with form and as free of words as any architectural book the MIT Press has ever published.

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The Ryzen 8000 desktop under the Zen 5 architecture would be codenamed Granite Ridge Sun, 30 May 2021 01:09:13 +0000

The Ryzen 8000 APUs are said to be codenamed Strix Point.

AMD has gradually downgraded its Zen 3 architecture through its various processor lines (Ryzen 5000 office, APU, EPYC Milan…) during the previous months. The company remains quite discreet for the moment on its plans for the future, which we have nevertheless discovered thanks to several leaks. The indiscretion of the day projects us in a few years, in the era of chips under the Zen 5 architecture, in other words the Ryzen 8000. The slide above mentions this designation as well as two code names, Granite Ridge and Strix Point. ; the first would designate the Ryzen 8000 office lacking an integrated graphics solution, the latter has an APU.

This isn’t the first time we’ve been talking about the Ryzen 8000 – about a month ago, we learned that AMD may adopt a big.LITTLE design for this lineup, like what Intel will soon be offering with its twelfth generation. from Core, Lake Alder.

AMD AM5 socket: LGA-1718 and DDR5, but not PCIe 5.0?

Zen 5: APU EPYC Turin, Ryzen 8000 Granite Ridge and Ryzen 8000 Strix Point

To put it in perspective, the Ryzen 8000 office It would benefit, as mentioned above, from the Zen 5 processor cores, synonymous with 3nm engraving. In the current state of our knowledge, we assume that they will succeed the Ryzen under the Zen 4 architecture registered at 5nm codenamed Raphael, themselves succeeding the current Ryzen 5000 Vermeer (the hypothesis of a Zen 3+ generation at 6 nm Without However, the interposition between the two is not excluded). On the APU side, the Rembrandts or Pheonixes must transmit Cézanne’s APUs; Then came Strix Point. Finally, for server processors, after EPYC 7004 Genoa processors, it would be EPYC 7005 Turin. As for the Threadripper, we are still waiting for those on the Zen 3 architecture.

Scope / Architecture 7 nm Zen2 7 nm Zen3 6 nm Zen3 + Zen4 5 nm 3 nm Zen5
EPYC Rome Milan Genoa Turin
Ryzen HEDT Castle peak Chagall Determined Determined Determined
Ryzen processor Matisse Vermeer Warhol Raphael Granite Ridge
Ryzen APU Renoir / Lucienne Cezanne / Barceló Rembrandt Phoenix Strix point

Looking at the timeline, there is a general consensus that Zen 4 processors won’t hit the market until next year. So don’t wait for the Ryzen 8000 until 2023.

Source: Tom’s Hardware USA

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[#WeFACE] Dutch architect says local architectural projects reusing old materials should go global Sat, 29 May 2021 07:01:00 +0000

Dutch architect Jos de Krieger (Jos de Krieger)

Dutch architect Jos de Krieger, who has been a partner in architecture firm Superuse Studios since 2006, stressed the importance of going global with local architectural projects that reuse old and used materials.

“The construction industry is one of the biggest polluters and the reuse of building materials can help reduce the environmental footprint,” De Krieger said in a recent email interview with The Korea Herald.

He explained how projects that reuse old and used materials can help preserve our environment.

“By giving a material new life, you extend its life and thus reduce the environmental impact of that material,” he said. “In some cases, the additional years may even be more than the original use. It is an important part of cascading materials and it will help to create a circular economy. “

Superuse Studios started in 1997 as architects in 2012, creating small architectural interventions and reusing items such as washing machines, cable reels and car windows. In 2009 the company started building an entire house from salvaged materials and in 2012 it changed its name to Superuse Studios.

Today, De Krieger’s company focuses primarily on creating architecture using circular and sustainable design, in the belief that design is part of a circular process as opposed to a linear process.

To pursue its mission of creating a new building while respecting the environment, his company is working on multiple local projects that involve the collection of used materials nearby.

Harvesting is a popular architectural term that refers to the process of urban mining to salvage used materials, according to De Krieger.

“Over the years, we have completed many projects at different scales, ranging from a single family home Villa Welpeloo to a playground without rotor blades,” he said.

Villa Welpeloo is made from reused materials.  (Allard van der Hoek)

Villa Welpeloo is made from reused materials. (Allard van der Hoek)

Villa Welpeloo in Enschede, The Netherlands is a villa designed for a couple with a collection of drawings and graphic art. The main structure is made of steel beams that were previously part of a machine used for textile production, an industry that was once very important in the region. The wooden slats, which were originally used for cable reels at TKF, a local factory that produces cables, were collected to be used as the facade of the villa.

The playground, called Wikado, is one of Superuse Studios’ Blade Made projects. The Netherlands-based company has created mazelike structures of tunnels and towers that children can play with, from discarded wind turbine parts.

The playground called Wikado was created from parts of discarded wind turbines.  (Denis Guzzo)

The playground called Wikado was created from parts of discarded wind turbines. (Denis Guzzo)

“Currently, we are also working on larger housing projects of 20 to 50 houses,” he said. “In addition to this, we also research the topic of reuse and develop tools that support our work and the architectural community as a whole.”

De Krieger also addressed misconceptions about structures built from reused materials.

“In general, the designs made by Superuse are not just about reuse, but about creating a functional and welcoming space that just happens to be made of trash. In some cases, people won’t even recognize that it’s being reused, ”he said.

De Krieger also added that these buildings can cost less to build.

“The hardware is generally cheaper,” he says.

However, he said the overall cost may depend on labor costs, which are usually a bit higher for construction with reused materials.

“In the end, it usually comes down to being about the same, in some cases it can even be cheaper,” he added.

De Krieger also stressed the importance of the role of government in making the construction of buildings from reused materials more cost effective.

“It would help create a level playing field for the circular architecture if (new) resources were taxed more heavily while reducing the tax on labor,” he said.

The Dutch architect added that his company is currently challenging government regulations with Project Ex’tax, an independent think tank that works to update tax systems to tackle global challenges such as climate disruption, the risks of resource supply and unemployment.

Besides the question of taxation, the Dutch designer also mentioned another obstacle to the creation of an architecture with reused materials.

“Building a new structure comes with regulations and permits, so it’s always a time-consuming process. With the increasing scarcity of materials, we predict that in the future material reuse may be faster than traditional material deliveries, ”he said.

In the interview, he also shared how he became interested in more environmentally friendly architectural projects.

“For me personally, it started when one of the founders gave a talk at TU Delft, showing the Duchi shoe store they were making with salvaged car windows,” he said. “Then and there, I decided to do an internship at 2012Architecten, as Superuse was called until 2012, to learn more about reuse in architecture. I never left the company because it was so much fun to find new life for materials that others see as waste.

By Song Seung-hyun (

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Researchers determine new classification system for DNA architecture across the lifespan Fri, 28 May 2021 17:41:32 +0000

This work was generated from several initially independent research efforts. For some time now, scientists on the DNA Zoo team have been trying to classify how chromosomes fold to fit into the nucleus of cells of different species across the tree of life.

DNA Zoo is an international consortium that includes institutions such as Baylor College of Medicine, the Center for Theoretical Biological Physics (CTBP) at Rice University, the University of Western Australia and SeaWorld, supported by the National Science Foundation.

First, the team conducted in situ Hi-C on 24 species, representing all chordate subphyla, the seven vertebrate classes, seven of the nine major animal phyla, as well as plants and fungi. Together, these genomic assemblies provide a comprehensive overview of nuclear organization since the last common ancestor of all eukaryotes.

The maps revealed four features of the nuclear architecture found on the chromosomes:

  • increased frequency of contact between loci on the same chromosome
  • prominent contacts between centromeres
  • prominent contacts between telomeres
  • X shape on the chromosome map

To identify these characteristics impartially, the team developed an aggregated chromosome analysis (ACA), a method in which the contact cards for each chromosome are rescaled and summed, then used to score each characteristic. The characteristics have been divided into two groups, based on their coexistence. Type I included clustering of centromeres, clustering of telomeres, and a telomere-to-centromere axis. Type II included only the chromosomal territories.

“Whether we were looking at worms or sea urchins, sea squirts or corals, we kept seeing the same folding patterns coming,” said co-author Olga Dudchenko, PhD, a member of the Center for Genome Architecture at Baylor and CTBP. “In some species, the chromosomes are organized like the pages of a printed newspaper, with the outer margins on one side and the middle folded on the other. And then in other species, each chromosome is crumpled into a small ball.”

Science according to which the nuclear arrangement in a human cell can be transformed into that typical of a fly. “/>

Biologists from Baylor College of Medicine, the Netherlands Cancer Institute and Rice University have shown in a study that the nuclear arrangement in a human cell can be transformed into that typical of a fly. Illustration courtesy of Evgeny Gromov.

To further explore these differences, the team developed an algorithm, called 3D-DNA Phaser, to assign variants to individual homologues (related genes), producing chromosomal length haploblocks for multiple species (segments with very little recombination). . The analysis revealed that features of the genome’s architecture appear and disappear over billions of years, as the lineages switch between types.

The team found that type I species lacked a subunit of the condensin II complex, which promotes mitotic chromosome compaction. They also noted that Type I architectural features and the loss of Condensation II subunits appear to have co-evolved repeatedly over time. Analysis showed that condensin II strengthens chromosomal territories or counteracts type I characteristics.

Humans exhibit a type II genomic architecture, with strong chromosomal territories and no type I characteristics.

Meanwhile, an independent team in the Netherlands had discovered something unexpected.

“I was experimenting with a protein called condensin II, which we knew plays a role in cell division,” said author Claire Hoencamp, a doctoral student at the Dutch Cancer Institute. “But we observed the strangest thing: when we mutated the protein in human cells, the chromosomes completely reorganized themselves. It was baffling!”

The two teams met at a conference where they realized they had stumbled upon a way to convert human cells from one nuclear type to another.

“When we looked at the genomes studied at the DNA Zoo, we found that evolution had been our experience many times before! When mutations in one species break down condensin II, they usually reverse the entire architecture of the nucleus, ”Rowland said.

“So we had a puzzle,” said senior author Erez Lieberman Aiden, PhD, associate professor of molecular and human genetics at Baylor and co-director of DNA Zoo. “The data implied that during evolution, species can switch from one type to another. We asked ourselves: what is the control mechanism? Would it be possible to change one type of nucleus into one? other in the laboratory? “

To explore this possibility, they performed Hi-C in situ on Hap1 cells lacking the condensin II CAP-H2 subunit. These cells exhibited weaker chromosomal territories and much stronger contacts between centromeres. Immunofluorescence microscopy revealed that in cells, centromeres are grouped together. Thus, the disruption of condensin II transforms the folding of the human genome into a type I configuration.

“Our simulations showed that by destroying Condensin II, you could rearrange a human nucleus to resemble a fly nucleus,” said José Onuchic, PhD, co-director of CTBP, which includes collaborators at Rice, Baylor, Northeastern University. and other institutions. in Houston and Boston.

“We started with an incredibly broad survey of 2 billion years of nuclear evolution,” said author Sumitabha Brahmachari, PhD, postdoctoral researcher in Onuchic’s lab at CTBP. “And we’ve found that it all comes down to a simple mechanism, which we can simulate and summarize, on our own, in a test tube. This is an exciting step on the road to a new kind of genome engineering – in 3D! “

Do you have a unique perspective on your research related to genomics or evolutionary biology? Contact the publisher today to find out more.

Related reading

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Tiny prefab architectural designs that prove this trend is the future of modern architecture! Thu, 27 May 2021 23:30:35 +0000

Prefabricated architecture has recently gained a lot of popularity and momentum! Essentially, it involves constructing buildings or constructing various components at a particular location, which is best suited for construction, and then when completed, transporting it to the final site or location. Prefabricated architectural designs have a multitude of advantages: they reduce costs, ensure that projects are more sustainable and efficient, and they also prioritize and pay attention to simplicity and modularity. And we have selected a collection of our favorite prefabricated models for you – from cozy cubicles to home office modules! These prefabricated designs are part of a growing trend in modern architecture and could be the future of it too!

The cabins allow you to get out and at the same time be socially distant, making it perfect for a post-pandemic getaway. Italian architects Massimo Gnocchi and Paolo Danesi are probably also eager to take advantage of some downtime and therefore created the Mountain Refuge to express their desire to travel. It is a wooden, square, prefabricated cabin with an angular roof. While the geometric cabin is a structural contrast to its natural setting, it still fits in well while showing off its modern design. “The project acts as a contemporary interpretation of old traditional mountain huts, bringing architectural character and spatial quality,” explain the designers. The wooden cabin comes in different modules and each has the ability to be flexible and expandable. It is made to be compact and optimize space while taking up the least amount of nature.

Designed by Nestron, Cube Two is a 263 square foot home designed for the future and smart living. This modern compact house is a prefabricated structure which is already fitted with the latest household appliances which can all be controlled by an AI assistant named Canny. The exterior has smooth curved corners which give it a homey feel and the interior provides enough space for a family of four to live comfortably with two bedrooms and an open living room. To make it more spacious, there is a skylight that runs through the ceiling and floods the space with natural light, and also provides a beautiful backdrop of the night sky.

Prefabricated cabins such as GROVE CAB, designed by Valerii Shcherbak, help make nature getaways much more comfortable and that much more accommodating. This new type of architecture is gaining a lot of popularity in Europe and this is no surprise. Prefabricated cabins are built with a focus on simplicity and modularity. Since Shcherbak’s cabin is constructed from sturdy lumber and panels, every component of GROVE CAB is designed for a familiar and intuitive construction, and the light, natural wood tones help open up every room. The cabin comes in two modules: the first contains a living room or recreation area and your bedroom, and the second includes a kitchen, bathroom and an outdoor patio. The two units are connected where the frames of the two module corridors meet, creating a space that resembles a one bedroom house.

Woonpioniers, an Amsterdam-based architecture and design studio, created Indigo, a modular building system that designs homes to replicate any of your dreams. Depending on the house you want to build with Woonpioniers, the structure and shape of Indigo may vary. Recently, Lia Harmsen collaborated with Woonpioniers to design her prefabricated workspace for sculpture. The custom finished two story home measures 861 square feet and features fixed time construction practices that produce a beautiful, curved interior leading from wall to ceiling. The home’s fixed-end moment frame provides an open-air floor plan, giving full access for the building’s interior layout to take shape, leaving behind the spatial restriction of support beams and partitions.

Named Kvivik Igloo, the tiny prefabricated houses perched on top of the Kvivik Hills, overlooking the bay and surrounding mountains. Designed to look like tiny hobbit cottages, each Igloo Kvivik is built with a hexagonal frame and design elements meant to echo the past. Lined with asphalt panels, Kvivik’s Igloos can sprout grass and greenery from their rooftops and sides to truly transport residents to their favorite hobbit fairy tale. The living igloo roof not only adds to its charm, but also adds to the sustainability factor of the cottage, creating an elevated nesting place for birds and woodland creatures. Highlighting their sustainability efforts, builders use passive house building practices and natural materials to build Kvivik igloos, including wood, glass, aluminum and rubber.

Studio Puisto, an interior design studio based in Finland, collaborated with furniture brand Made By Choice and design company Portos Demos to create Space of Mind, a prefabricated modular micro booth to be installed anywhere in order to that customers can go from their home office to an off-grid mountain studio for peace and productivity. The modular cabin can be placed anywhere accessible by helicopter or crane and designed as a peaceful working studio, a vibrant fitness center, or a comfortable hotel-style bedroom. Studio Puisto, which is turning its micro cabin design into a micro-hospitality solution, even has plans underway to create an app for reservations and keyless entry and to build another micro cabin equipped with a sauna. .

The Majamaja Wuorio, built by Pekka Littow of Littow Architects, is described as an eco-cabin for its use of green energy storage and a closed-loop wastewater treatment system. Pekka Littow’s Majamaja concept was born out of life on the Finnish archipelago and essentially speaks of a building tradition that prioritizes harmony between humans and nature. Majamaja Wuorio units are prefabricated, transportable and using off-grid technologies such as solar panels and a recirculating water treatment system, the units can be located anywhere. The small cabin’s closed-loop water treatment system collects both rainwater and humidity from the air for storage, then sends it to the built-in water purification system for residents use it in the shower, kitchen or bathroom.

This pod is called “ My Room in the Garden ” because that’s exactly what it is and we don’t want to leave space for confusion as we all try to minimize our per-my-last- E-mail. The outer structure of the carrycot is made of weather-resistant aluminum and the interior has been designed in birch. To tone down that claustrophobic feeling, there are floor-to-ceiling windows that let in plenty of natural light. As mentioned earlier, you are the boss and therefore this module is fully customizable to fit your existing space. Since this is a modular, pre-fabricated system, you can build your pod to optimize your backyard or transmission without having to move anything.

Modern-Shed, a leader in innovative, sustainable prefabricated structures, heard our 11:11 wishes and designed Dwelling on Wheels, or DW for short. Their Housing on Wheels is a tiny 220 square foot house on wheels that buyers can take with them on the road and set up on nearby shores or riverbeds for overnight stays and views. Built to withstand varying climates and temperatures, a steel rib cage and metal standing seam siding surround the exterior of the DW for a durable, weatherproof finish. Completing the design of the industrial cottage, accents of red cedar wood warm the walls, eaves and even the canopy of the cottage which hangs over a durable iron wood deck, accessible through the door. double glazed glazed gable of the house.

Brette Haus prefab cabins are literally shipped to your location on the back of a trailer. In 3 hours, the house is placed on site, unfolded and secured in place, transforming it from a strange wooden cardboard box into a living cabin with between 22 and 47 square feet of space (depending on the cabin, a variant ). Each cabin takes approximately 8 weeks to manufacture and is made entirely from carbon neutral, weather resistant and durable cross laminated timber. There is no need for a permanent foundation… the cabins can be easily unfolded on any level ground before being secured in place using screw piles. Cab hinges can survive up to 100 folding cycles.

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AI testing: going beyond DFT architectures Thu, 27 May 2021 07:06:44 +0000

The size of massive, highly parallel AI processor chips has a significant impact on design and testing methodologies.

Every day, more and more applications are deploying an artificial intelligence (AI) system to increase automation beyond traditional systems. The continued growth in computing demands for AI systems is forcing designers to develop massive, highly parallel AI processor chips. Their large sizes and types of applications have a significant impact on their design and testing methodologies. With thousands of repeating cores, as well as IP integrated into a system on a chip (SoC), new architectures and design-for-test (DFT) methodologies are needed to maximize the quality of silicon tests while minimizing the costs of testing. test. In addition, AI chips used in safety critical applications, such as autonomous driving, require the highest quality manufacturing testing to achieve less than one defective part per million (DPPM) and need DFT structures to ensure the correct and safe operation of the chips. during system operation. However, adding such DFT logic to the design further increases the size of already large chips.

Leveraging a hierarchical testing methodology is ideal for AI designs. It uses a divide and conquer approach by breaking the design into smaller hierarchical partitions for DFT approval, which includes the following: DFT insertion, test mode setup, model generation, and verification. An AI design can contain multiple levels of hierarchy, each with repeated DFT partitions, and each partition can be a single core or a group of cores depending on the DFT architecture, as shown in Figure 1. With a methodology Hierarchical testing, the DFT trust for each unique partition at a hierarchical level is performed once and reused in all replicated instances. The exact process is repeated at each hierarchical level to gain DFT approval for the entire design, as shown in Figure 2. After completing the DFT at the partition level, configuration and test mode patterns corresponding are carried to the chip level to activate application with automatic test equipment (ATE).

Fig. 1: Typical AI chip showing DFT partitions at different hierarchical levels.

Fig. 2: Hierarchical testing allows DFT disconnection and reuse of partitions at each hierarchical level.

One of the most notable benefits of this methodology is significantly increased productivity and reduced compute resource requirements. This is because the DFT approval task for each unique partition can be performed independently and in parallel with other partitions, using much smaller computing machines than needed for the flat DFT approval methodology, as shown. figure 3.

Fig. 3: Increased productivity and reduced compute resources thanks to a hierarchical test methodology.

In general, AI testing requirements often conflict with stringent power, performance, and area (PPA) requirements. With discrete test streams, DFT logic is generated and added to the design logic without considering its impact on the physical design (PD), and the DFT logic is analyzed in the same way as any other functional logic for the implemented during the PD process. This lack of consideration of DFT logic in the technology for implementing the physical design often results in a degraded PPA for the entire design (user more logical DFT) or a significant delay in the realization of the design. convergence of design. In some cases, a modification of the DFT architecture is necessary to resolve these problems. The degradation becomes more pronounced in the case of AI designs, as a suboptimal DFT logic implementation in one core, made worse when replicated across thousands of cores, has a severe impact on the overall PPA. of the chip.

Fig. 4: Obsolete and discrete test flow with isolated DFT and physical design process.

For these large and complex AI chips, it is easy to understand that just as the DFT architecture and methodologies are important to achieving test goals, a DFT implementation that is physically aware is crucial to minimizing the load on the effort. physical design to achieve optimal PPA. . Therefore, AI chip designers must simultaneously deploy test technology that addresses the combined challenges of optimal DFT architecture and optimal implementation.

Effective and efficient test solutions must optimize the physical implementation of DFT logic to take full advantage of appropriate test methodologies and architectures for AI designs. In addition to supporting hierarchical testing, advanced DFT technologies unify DFT and physical implementation engines into a single, transparent flow for physically-aware DFT design and implementation. Some of the important techniques used by these test solutions include:

Targeted logical and physical optimizations of DFT logic such as automatic distribution of test compression block for placement, intelligent routing of DFT logic, reclassification of test compression connections, clock network optimizations, etc. .

Fig. 5: High sweep compression with congestion optimization (heat map).

Geolocated test points for improved routing and reduced number of models.

Fig. 6: Traditional test points vs. location sensitive test points.

Order based on the location of elements in the scan chain to reduce congestion.

Fig. 7: Congestion with sutured scan cells without and with physical information.

Physically conscious casing cells based on the location of the center pins when inserting the isolation casing.

As the test goals for high-quality, low-cost testing of AI chips become increasingly difficult, test solutions must include a physically aware DFT implementation to enable ideal architectures, time-saving methodologies time and optimal PPA. The application of discrete DFT technologies and flows detached from the current implementation technology invites below average results or a huge effort to compensate. Advanced test technologies that address the challenges of DFT and physical implementation as a unified goal are needed to meet the growing expectations of today’s design and test teams.

Rahul singhal

(All posts)

Rahul Singhal is Product Marketing Manager in the Hardware Analytics & Test group at Synopsys.

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Biden revamps architecture panel, more art news – Wed, 26 May 2021 13:46:00 +0000

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PRESIDENT BIDEN APPOINTED FOUR PEOPLE at Fine Arts Commission, who provides advice on the design of federal buildings in Washington, DC, NPR reports. The decision, which will diversify its membership, comes a day after the president expelled four members appointed by President Trump. Trump’s appointments had made the seven-member board of directors all white and all male. The new members proposed are architects Peter Cook, Hazel Ruth Edwards, and Billie Tsien, and the designer and town planner Justin garrett moore. The president ousted from the commission, Justin shubow, Told Artnet news, “Nothing like this has ever happened in the 110-year history of the Fine Arts Commission.” Artnet notes that Shubow is involved in the National Society of Civic Art, who helped draft a Trump executive order to promote neoclassical buildings. (This has since been revoked.) Shubow called Biden’s actions “an attack on classical architecture.”

Related Articles

A SURVEY OF 10 GREAT MUSEUMS IN SOUTHERN CALIFORNIA speak Los Angeles Times found that only 19.5% of their board members are not white, a stark contrast to the nearly 74% in LA County who are not white. Of the 334 board seats covered by the report, 18 were occupied by blacks. That’s 5.4%, while the county’s population is 9% black. Meanwhile, the Art journal has a look at how American museums have attempted to improve the diversity of their staff, audiences, and programming as part of the racial calculation that followed the murder of George floyd. One glaring statistic cites the report: Association of Art Museum Directors estimates that about 85% of the directors of its 227 members are white.

The Digest

Architect and historic curator Charles Cassell, who was a vocal advocate for Washington state, has died at the age of 96. A World War II veteran, he opposed the design of the World War II Memorial in the city, saying it would “desecrate the National Mall.” ” [The Washington Post]

Artist Jackie Matisse, who has created freewheeling kite works and collaborated with such figures as composer David Tudor and filmmaker Molly Davies, has died at age 90. mother, Alexina “Teeny” Duchamp, after her divorce from the art dealer Pierre Matisse. [Tilton Gallery/Art Daily]

Newfields, home of the Indianapolis Art Museum, has listed the residence he provided to its director. The asking price is $ 2.2 million. The broker responsible for the listing said the institution was in talks to sell even before its boss, Charles Venable, resigned in February amid controversy. [Indianapolis Business Journal]

Luxury giant (and ARTnews Top 200 Collector) François Pinault spoke about his last private museum, the Bourse de Commerce in Paris, and his life with the Time. “Humility has to be worked on every day with a pumice stone,” he said. “Ego is something that grows if you don’t apply a weedkiller.” Pinault also detailed his long-standing friendship with artist David Hammons. [The New York Times]

Speaking of Hammons, Alex Greenberger has a new overview of his work, which “longs for unknowability,” he writes. [Art in America]

The Contemporary Arts Museum Houston has appointed Allison Glenn as its next senior curator and director of public art. Glenn is from the Crystal Bridges Museum of American Art in Bentonville, Arkansas, where is Associate Curator of Contemporary Art. She also hosted the show honoring the life of Breonna Taylor at the Speed ​​Art Museum in Louisville, Kentucky. The position of Senior Curator of CAMH was last filled by Valerie Cassel Oliver, who left in 2017 to become Curator of Modern and Contemporary Art at the Virginia Museum of Fine Arts in Richmond. [Houston Chronicle]

Art fairs are slowly coming back, and now so are fashion shows. While many presentations at Milan Fashion Week in June will be digital affairs only, Giorgio Armani, Dolce & Gabbana and Etro are planning to host live events with an in-person audience. [Associated Press]

The Kicker

IN AUSTRALIA, TWO VETERAN ART DEALERS ARE DOWN their businesses. For a living and moving story in the Financial analysisjournalist Gabriella Coslovich speak with Nevin Hurst, 87 and Denis savill, 80, while selling their inventory and doing other closing duties. “It’s going to be sad, extremely sad, because it’s your life, and honestly, sincerely, it means more to me than money”, says Hurst, based in Hobart. Saville, who works in Sydney, has some sort of retirement bonus waiting for him, having wisely bought his three-story gallery in 1985, just 11 days before a capital gains law went into effect. He spent A $ 250,000 on it and advertised it for A $ 4.8 million (approximately US $ 3.74 million). “I don’t have to pay tax on it,” he said. [FR]

Thanks for the reading. Well see you tomorrow.

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